Sahih al-Bukhari 311Book 6, Hadith 16
حَدَّثَنَا مُسَدَّدٌ، قَالَ حَدَّثَنَا مُعْتَمِرٌ، عَنْ خَالِدٍ، عَنْ عِكْرِمَةَ، عَنْ عَائِشَةَ، أَنَّ بَعْضَ، أُمَّهَاتِ الْمُؤْمِنِينَ اعْتَكَفَتْ وَهْىَ مُسْتَحَاضَةٌ.
One of the mothers of the faithful believers (i.e. the wives of the Prophet (ﷺ) ) did I`tikaf while she was having bleeding in between her periods.